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PVALB Antikörper (C-Term)

PVALB Reaktivität: Human, Ratte WB, IHC (p) Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN374572
  • Target Alle PVALB Antikörper anzeigen
    PVALB (Parvalbumin (PVALB))
    Bindungsspezifität
    • 15
    • 7
    • 7
    • 4
    • 1
    • 1
    C-Term
    Reaktivität
    • 40
    • 36
    • 29
    • 15
    • 1
    Human, Ratte
    Wirt
    • 49
    • 20
    • 2
    • 1
    Ziege
    Klonalität
    • 43
    • 29
    Polyklonal
    Konjugat
    • 23
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PVALB Antikörper ist unkonjugiert
    Applikation
    • 40
    • 30
    • 26
    • 16
    • 16
    • 13
    • 13
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Sequenz
    C-GVDEFSTLVA ES
    Spezifität
    This antibody recognizes Parvalbumin.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Rat.
    Aufreinigung
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    Immunogen
    Peptide with sequence from the C Terminus of the protein sequence according to NP_002845.1.
    Top Product
    Discover our top product PVALB Primärantikörper
  • Applikationshinweise
    Peptide ELISA: 1/32000. Western Blot: 0.1-0.3 μg/mL. Approx 12 kDa band observed in Human Brain lysates (calculated MW of 12.2 kDa accordingto NP_002845.1). Approx 10-12 kDa band observed in rat skeletal muscle and in rat heart cells transfectedwith human PVALB, but not in untransfected rat heart cells. (1)
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    PVALB (Parvalbumin (PVALB))
    Andere Bezeichnung
    Parvalbumin alpha / PVALB (PVALB Produkte)
    Synonyme
    D22S749 antikoerper, PV antikoerper, Parv antikoerper, Pva antikoerper, PALB1 antikoerper, pvalb1 antikoerper, MGC107903 antikoerper, parvalbumin antikoerper, parvalbumin, gene 1 antikoerper, parvalbumin, gene 1 S homeolog antikoerper, PVALB antikoerper, Pvalb antikoerper, pvalb.1 antikoerper, pvalb.1.S antikoerper
    Hintergrund
    Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin. Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis (ALS) patents, parvalbumin immunoreactivity is specifically absent from neuron populations lost early in ALS.
    Gen-ID
    5816
    NCBI Accession
    NP_002845
    UniProt
    P20472
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