CD2BP2 Antikörper (N-Term)
Kurzübersicht für CD2BP2 Antikörper (N-Term) (ABIN374445)
Target
Alle CD2BP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- C-PKRKVTFQGV GDE
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Spezifität
- This antibody recognizes CD2BP2.
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Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse, Rat, Dog, Cow.
Species reactivity (tested):Human. -
Aufreinigung
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
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Immunogen
- Peptide from the N Terminus of the protein sequence according to NP_006101.1.
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Applikationshinweise
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Peptide ELISA: 1/32,000. Western Blot: 0.3-1.0 μg/mL. Detects a band of Approx 50 kDa in Human Lymph Node,Thymus and Tonsil lysates (Predicted Molecular Weight: 37.0 kDa).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store the antibody (in aliquots) at -20 °C.
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- CD2BP2 (CD2 (Cytoplasmic Tail) Binding Protein 2 (CD2BP2))
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Andere Bezeichnung
- CD2BP2
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Hintergrund
- CD2BP2 is an intracellular protein which binds to a site containing two PPPGHR segments within the cytoplasmic region of CD2. Mutagenesis and NMR analysis demonstrated that the CD2 binding region of CD2BP2 includes a 17 amino acid motif also found in several yeast and Caenorhabditis elegans proteins of unknown function. In Jurkat T cells, over expression of the isolated CD2BP2 domain binding to CD2 enhances the production of interleukin 2 on crosslinking of CD2 but not the T cell receptor.Synonyms: CD2 antigen cytoplasmic tail-binding protein 2, CD2 cytoplasmic domain-binding protein, CD2 tail-binding protein, KIAA1178
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Gen-ID
- 10421, 9606
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UniProt
- O95400
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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