BIRC7 Antikörper (C-Term)

Produktnummer ABIN374091

Der Ziege Polyklonal anti-BIRC7 Antikörper (ABIN374091) detektiert spezifisch BIRC7 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für BIRC7 Antikörper (C-Term) (ABIN374091)

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser BIRC7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BIRC7 Antikörper

Bindungsspezifität: C-Term

Sequenz: C-RAPVRSRVRT

Spezifität: This antibody is expected to recognise both reported isoforms of BIRC7 (as represented by NP_647478.1 and NP_071444.1)

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from C Terminus of the protein sequence according to NP_647478.1, NP_071444.1. Genename: BIRC7

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: Limit dilution 1: 4000. Western blot: 0.1 - 1.0 μg/mL. Experiments gave bands at approx 30 kDa and 30 kDa inhuman acute lymphoblastic leukaemia MOLT4 lysate after 0.3 μg/mL antibody staining. These bands correspond to the reported isoforms with calculated MW of 32.0 kDaaccording to NP_647478.1 and 30.0 kDa according to NP_071444.1.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu BIRC7

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Andere Bezeichnung: BIRC7 / LIVIN

Hintergrund: Livin is a novel member of the IAP protein family and contains a single baculoviral IAP repeat (BIR) domain and a RING finger domain and has two isoforms termed Livin alpha and Livin beta. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. The two isoforms of Livin appear to have different functions and tissue distributions.Synonyms: Baculoviral IAP repeat-containing protein 7, KIAP, Kidney inhibitor of apoptosis protein, Livin, MLIAP, Melanoma inhibitor of apoptosis protein, RING finger protein 50, RNF50

Gen-ID: 79444

NCBI Accession: NP_647478

UniProt: Q96CA5