Rab3 (N-Term) Antikörper

Antigen: Rab3

Epitope: N-Term

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN372708

Produktbeschreibung

Produktmerkmale: Synonyms: RAB3A, Rab-3A, RAB3B, Rab-3B, RAB3C, Rab-3C, RAB3D, Rab-3D, Ras-related proteinRab-3A, Ras-related protein Rab-3B, Ras-related protein Rab-3C, Ras-related proteinRab-3D

Gen-ID: 25531

Swiss-Prot: P63012

Immunogen: Peptide corresponding to amino acid residues from the N-terminal region of Rat Rab3,conjugated to keyhole limpet hemocyanin (KLH).

Kreuzreaktivität: Human, Maus, Ratte (Rattus), Xenopus laevis

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamilyhas 4 known isoforms: 3A, 3B, 3C, and 3D (Schluter et al. , 2004). These proteins areexpressed in highest concentrations in brain and endocrine tissues and involved inregulated exocytosis of hormones and neurotransmitters (Coppola et al. , 2002). Specifically, Rab3’s are thought to play a key role in presynaptic vesicle trafficking andpriming (Schluter et al. , 2006).

Spezifität: This antibody recognizes the ~27k Rab3 protein. Species Reactivity: Tested: Rat. Expected from sequence similarity: Human, Mouse, Xenopus and non-Human Primates.

Anwendungen

Applikationshinweise: Western blot: 1/1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Reinigung: Aff - Purified

Buffer: 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% Glycerol.

Lagerung: Store the antibody undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Beschränkungen: Nur für Forschungszwecke einsetzbar