Tamalin/GRASP Antikörper (C-Term)
Kurzübersicht für Tamalin/GRASP Antikörper (C-Term) (ABIN372659)
Target
Alle Tamalin/GRASP (GRASP) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- This antibody is specific for the ~95k GRASP protein.
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Kreuzreaktivität (Details)
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Species reactivity (expected):Bovine, Canine, Human and Mouse.
Species reactivity (tested):Rat. -
Aufreinigung
- Affinity Chromatography.
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Immunogen
- Peptide corresponding to amino acid residues from the C-terminal region of rat GRASP, conjugated to keyhole limpet hemocyanin (KLH).
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Isotyp
- IgG
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Applikationshinweise
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Western blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store the antibody undiluted (in aliquots) at-20 °C.
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- Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))
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Andere Bezeichnung
- GRASP
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Hintergrund
- PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).Synonyms: GRP1-associated scaffold protein, General receptor for phosphoinositides 1-associated scaffold protein
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Gen-ID
- 192254
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NCBI Accession
- NP_620249
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UniProt
- Q8R4T5
Target
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