SLC6A3 Antikörper (C-Term)

Produktnummer ABIN372613

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SLC6A3 in WB, IHC (fro) und DB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Non-Human Primate.

Kurzübersicht für SLC6A3 Antikörper (C-Term) (ABIN372613)

Target: SLC6A3 (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))

Reaktivität: Human, Maus, Non-Human Primate

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC6A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Dot Blot (DB)

Produktdetails anti-SLC6A3 Antikörper

Bindungsspezifität: C-Term

Spezifität: Specific for the ~88 kDa DAT protein in Western blots.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse and non-Human Primates.

Aufreinigung: Affinity Chromatography using a SulfoLink® column matrix to which the peptide immunogen was coupled.

Immunogen: Peptide from the intracellular C-terminus region of human Dopamine Transporter (DAT), conjugated to keyhole limpet hemocyanin (KLH).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot (1/1000) of SDS-solubilized Human and Mouse striatal samples. Immunohistochemistry (Frozen Sections, Formaldehyde Fixed Tissue): 1/1000 with Monkey(Macaque) brain sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at-20 °C. For long term storage at -80 °C is recommended.

Details zu SLC6A3

Target: SLC6A3 (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))

Andere Bezeichnung: SLC6A3 / DAT

Hintergrund: The dopamine transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001, Zhu et al., 2000, Zhu et al., 1999). Levels of DAT protein expression are altered by chronic drug administration (Wilson et al., 1996).Synonyms: DA transporter, DAT1, Sodium-dependent dopamine transporter, Solute carrier family 6 member 3

Gen-ID: 6531

NCBI Accession: NP_001035

UniProt: Q01959

Pathways: Dopaminergic Neurogenesis