Apolipoprotein D Antikörper (N-Term)
Kurzübersicht für Apolipoprotein D Antikörper (N-Term) (ABIN372486)
Target
Alle Apolipoprotein D (APOD) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- This antibody recognizes Apolipoprotein D (APOD).
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Kreuzreaktivität (Details)
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Species reactivity (expected):Human and Rat.
Species reactivity (tested):Mouse. -
Aufreinigung
- Immunoaffinity Chromatography.
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Immunogen
- Synthetic peptide corresponding to N-terminal residues of mouse APOD.
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Isotyp
- IgG
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Applikationshinweise
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Western Blot: 1 μg/mLImmunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0,5 mg/mL
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Buffer
- PBS containing 0.01 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Apolipoprotein D (APOD)
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Andere Bezeichnung
- Apolipoprotein D (Apo D)
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Hintergrund
- Apolipoprotein D (APO D), a glycoprotein involved in the human plasma lipid transport system. It is a progesterone binding glycoprotein of 24,000 dalton monomer molecular size, is a constituent of high density lipoprotein in plasma. The function of apolipoprotein D in the metabolism of plasma lipoproteins is unclear but the observation that this protein forms complexes with lecithin: cholesterol acyltransferase has led to the suggestion that apolipoprotein D may be involved in cholesterol esterification and transport of substrates and products of the reaction. Apolipoprotein D is expressed in a range of normal tissues including axillary apocrine glands, adrenal cortex and corpus luteum. Peripheral nerves, pituitary, testis, cerebellum and renal tubes are also positive. APO D was first isolated in large quantity as GCDFP 24, the major protein component of most human breast cyst fluids. In recent studies, Apo D immunoreactivity has been shown to be an early indicator of prostate cancer and advanced primary prostate tumors.Synonyms: APOD, Apo-D
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Molekulargewicht
- 21 kDa.
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Gen-ID
- 347
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NCBI Accession
- NP_001638
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UniProt
- P05090
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Pathways
- Platelet-derived growth Factor Receptor Signaling
Target
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