Integrin beta 7 Antikörper (PE)

Produktnummer ABIN371137

Der PE-konjugierte Ratte Monoklonal anti-Integrin beta 7 Antikörper (Klon DATK32) (ABIN371137) detektiert spezifisch Integrin beta 7 in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für Integrin beta 7 Antikörper (PE) (ABIN371137)

Target: Integrin beta 7 (ITGB7)

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Integrin beta 7 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: DATK32

Produktdetails anti-Integrin beta 7 Antikörper (PE)

Spezifität: This antibody is specific to mouse LPAM1 (Integrin alpha 4 beta 7). It recognises a conformational epitope on the heterodimer.

Produktmerkmale: Synonyms: Integrin beta-P, M290 IEL antigen, ITGB7, LPAM-1, LPAM1, Lymphocyte Peyer PatchAdhesion Molecule

Immunogen: AKR/Cum mouse spontaneous T lymphoma cell line TK1. (Ref. 1)

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: < / = 0.1 μg/10^6 cells. (Ref.1-4)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative and a stabilizing agent.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Integrin beta 7

Target: Integrin beta 7 (ITGB7)

Andere Bezeichnung: Integrin beta-7

Hintergrund: The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as Integrin alpha 4 beta 7 is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. (Ref.1-4) The Monoclonal antibody DATK32 has been shown to be useful for studies of the induction of homotypic cellular aggregation and the blockade of binding to cell adhesion molecules. (Ref.1)Synonyms: Adhesion Molecule, ITGB7, Integrin beta-P, LPAM-1, LPAM1, Lymphocyte Peyer Patch, M290 IEL antigen

Gen-ID: 16421

UniProt: P26011

Pathways: Integrin Complex