Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

HDAC4 Antikörper (pSer632)

HDAC4 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN362216
  • Target Alle HDAC4 Antikörper anzeigen
    HDAC4 (Histone Deacetylase 4 (HDAC4))
    Bindungsspezifität
    • 15
    • 14
    • 11
    • 9
    • 9
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer632
    Reaktivität
    • 116
    • 52
    • 35
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 104
    • 13
    • 1
    Kaninchen
    Klonalität
    • 104
    • 14
    Polyklonal
    Konjugat
    • 74
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HDAC4 Antikörper ist unkonjugiert
    Applikation
    • 90
    • 51
    • 29
    • 16
    • 14
    • 13
    • 13
    • 10
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    The antibody detects endogenous level of HDAC4 only when phosphorylated at serine 632.
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    Immunogen
    Peptide sequence around phosphorylation site of pSer632 (A-Q-S (p) -S-P) derived from Human HDAC4. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
    Isotyp
    IgG
    Top Product
    Discover our top product HDAC4 Primärantikörper
  • Applikationshinweise
    Western blotting: 1:500-1:1000  
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Lim, Luo, Koh, Yang, bin Abdul Kadir, Tan, Ye, Wang, Melamed et al.: "Distinct mechanisms involving diverse histone deacetylases repress expression of the two gonadotropin beta-subunit genes in immature gonadotropes, and their actions are overcome by ..." in: Molecular and cellular biology, Vol. 27, Issue 11, pp. 4105-20, (2007) (PubMed).

  • Target
    HDAC4 (Histone Deacetylase 4 (HDAC4))
    Andere Bezeichnung
    HDAC4 (HDAC4 Produkte)
    Synonyme
    CG1770 antikoerper, DHDAC4 antikoerper, Dmel\\CG1770 antikoerper, GC1770 antikoerper, HDAC antikoerper, HDAC4a antikoerper, dHDAC4 antikoerper, dmHDA405 antikoerper, hdac4 antikoerper, dana_GLEANR_19966 antikoerper, DanaGF18710 antikoerper, GF18710 antikoerper, HDAC4 antikoerper, AHO3 antikoerper, BDMR antikoerper, HA6116 antikoerper, HD4 antikoerper, HDAC-4 antikoerper, HDAC-A antikoerper, HDACA antikoerper, 4932408F19Rik antikoerper, AI047285 antikoerper, wu:fa96d08 antikoerper, wu:fc56f08 antikoerper, zgc:152701 antikoerper, histone deacetylase 4 antikoerper, hypothetical protein antikoerper, Histone deacetylase 4 antikoerper, GF18710 gene product from transcript GF18710-RC antikoerper, PTRG_03699 antikoerper, PGTG_15512 antikoerper, HDAC4 antikoerper, Dana\GF18710 antikoerper, Hdac4 antikoerper, hdac4 antikoerper
    Hintergrund
    Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
    Molekulargewicht
    140 kDa
    NCBI Accession
    NP_006028
    UniProt
    P56524
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
Sie sind hier:
Kundenservice