Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2) Antikörper

Antigen: Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2)

Synonyme: IRK1, LQT7, SQT3, HHIRK1, KIR2.1, HHBIRK1, Kcnf1, Kir2.1

Klonalität: Monoklonal (S112B-14)

Wirt: Maus

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB), Immunhistochemie (IHC)

Produktnummer: ABIN361769

Produktbeschreibung

Produktmerkmale: Detects ~45kDa. No cross-reactivity against Kir2.2 or Kir2.3

Weitere Bezeichnung: Kir2.1

Gen-ID: 16518

Swiss-Prot: P35561

Immunogen: Fusion protein amino acids 41-64 and 189-428 of mouse Kir2.1, accession number NP_032451.

Format: Liquid

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: S112B-14

Beschreibung: The Kir2.1 inward-rectifier potassium ion channel is encoded by the KCNJ2 gene. A defect in this gene is associated with Andersen-Tawil syndrome.
Synonyms: HHBIRK1, HHIRK1, HIRK 1, IRK1, KCNJ2, LQT7, SQT3, potassium inwardly rectifying channel J2

Spezifität: ~55kDa. No cross reactivity against Kir2.2, or Kir2.3. Species cross-reactivity: Human, Mouse, Rat.

Sensitivität: 1 µg/mL of SMC-310 was sufficient for detection of Kir2.1 in 10µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Anwendungen

Applikationshinweise: 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF)

Konzentration: 1 mg/mL

Reinigung: Protein G purified

Buffer: PBS pH7.4, 50% glycerol

Lagerung: -20 °C

Storage Shipping Temp Max: Blue Ice or 4 °C

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Kir2.1 (S21-32), Human hippocampus

Publikationen

Publikationen: Donaldson, Yoon, Fu et al.: "Andersen-Tawil syndrome: a model of clinical variability, pleiotropy, and genetic heterogeneity." in: Annals of medicine, Vol. 36 Suppl 1, pp. 92-7, 2004 (PubMed).