KCNQ1 Antikörper (AA 2-101)
Kurzübersicht für KCNQ1 Antikörper (AA 2-101) (ABIN361766)
Target
Alle KCNQ1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 2-101
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Spezifität
- Detects ~75 kDa.
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Kreuzreaktivität
- Hamster, Human, Maus, Ratte
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Aufreinigung
- Protein G Purified
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Immunogen
- Fusion protein amino acids 2-101 of human KCNQ1
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Isotyp
- IgG1
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Applikationshinweise
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- WB (1:1000)
- IHC (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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Kommentare
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1 μg/ml of ABIN361766 was sufficient for detection of KCNQ1 in 10 μg of COS-1 cell lysate transiently expressing KCNQ1 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C
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- KCNQ1 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1))
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Andere Bezeichnung
- KCNQ1
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Hintergrund
- Kv7.1 (KvLQT1) is a potassium channel protein coded for by the gene KCNQ1. Kv7.1 is present in the cell membranes of cardiac muscle tissue and in inner ear neurons (1) among other tissues. In the cardiac cells, Kv7.1 mediates the IKs (or slow delayed rectifying K+) current that contributes to the repolarization of the cell, terminating the cardiac action potential and thereby the heart's contraction (2, 3).
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Gen-ID
- 3784
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NCBI Accession
- NP_000209
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UniProt
- P51787
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Pathways
- Negative Regulation of Hormone Secretion, Sensory Perception of Sound
Target
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