CACNA1C Antikörper (AA 1507-1733)

Produktnummer ABIN361759

Dieser Maus Monoklonal Antikörper detektiert spezifisch CACNA1C in IHC, WB, IP, IF, ICC und AA. Es zeigt Reaktivität gegenüber Proben von Kaninchen.

Kurzübersicht für CACNA1C Antikörper (AA 1507-1733) (ABIN361759)

Target: CACNA1C (Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))

Reaktivität: Kaninchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CACNA1C Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Antibody Array (AA)

Klon: S57

Produktdetails anti-CACNA1C Antikörper

Bindungsspezifität: AA 1507-1733

Spezifität: Detects ~240 kDa (varies with cell background due to glycosylation).

Kreuzreaktivität: Hamster, Human, Maus, Ratte

Aufreinigung: Protein G Purified

Immunogen: Fusion protein amino acids 1507-1733 (intracellular carboxyl terminus) of rabbit Cav1.2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• IHC (1:1000)
• ICC/IF (1:100)
• IP (1:200)
• optimal dilutions for assays should be determined by the user.

Kommentare:

1 μg/ml of ABIN361759 was sufficient for detection of Cav1.2 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Details zu CACNA1C

Target: CACNA1C (Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))

Andere Bezeichnung: Cav1.2

Hintergrund: Cav1.2 is a cardiac L-type calcium channel, and is important for excitation and contraction of the heart (1). It may be associated with a variant of Long QT syndrome called Timothy's syndrome (2, 3) and also with Brugada syndrome. Some references also suggest it is related to bipolar disease as well (3).

Gen-ID: 100101555

NCBI Accession: NP_001129994

UniProt: P15381

Pathways: Hormone Transport, Carbohydrate Homeostasis