GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP) Antikörper

Antigen: GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP)

Synonyme: tamalin, TAMALIN, GRASP

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN361431

Produktbeschreibung

Weitere Bezeichnung: GRASP

Format: Affinity-purified

Beschreibung: PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000). Anti-GRASP Western blot of rat cerebellar lysate showing the specific immunolabeling of the ~95k GRASP protein.

Spezifität: Specific for the ~95k GRASP protein.

Anwendungen

Applikationshinweise: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Reinigung: Prepared from rabbit serum by affinity purification via chromatography on an affinity column prepared with the C-terminal peptide used as antigen.

Lagerung: Store at -20 °C, stable for 1 year

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blots of rat cerebellar lysate showing the specific immunolabeling of the ~95k GRASP protein.