Tyrosine Hydroxylase (TH) Antikörper

Antigen: Tyrosine Hydroxylase (TH)

Synonyme: TH, TyHyd, GB15303, th, LOC100219119, LOC446095, 2nd copy, Th, TYH, DYT14, DYT5b, The, DH65B, DTH, Pale, VII, dTH65B, pale/ple, DmelCG10118, CG10118

Klonalität: Polyklonal

Wirt: Schaf

Reaktivität: Säugetiere

Applikation: Western Blot (WB), Immunfluoreszenz (IF), Immunhistochemie (Gefrierschnitte) (IHC (fro))

Produktnummer: ABIN361414

Produktbeschreibung

Weitere Bezeichnung: Tyrosine Hydroxylase

Format: Affinity-purified

Beschreibung: Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson?s disease and drug abuse (Kish et al., 2001, Zhu et al., 2000, Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000, Salvatore et al., 2001). Anti-Tyrosine Hydroxylase Western blot of 10 ug of rat caudate lysate showing specific immunolabeling of the ~60k tyrosine hydroxylase protein.

Spezifität: Specific for the ~60k tyrosine hydroxylase protein.

Anwendungen

Applikationshinweise: Recommended Dilution: WB: 1:1000 IF (frozen sections, unpublished observations): 1:1000 IHC (frozen sections, unpublished observations): 1:1000 Quality Control: Western blots performed on each lot.

Reinigung: Prepared from sheep serum by affinity purification using a column to which immunogen was coupled. The antibody is predominantly of the IgG1 subclass.

Lagerung: Store at -20 °C, stable for 1 year

Forschungsgebiet: Krebs, Aminosäuren, Enzyme

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blots of 10 ug of rat caudate lysate showing specific immunolabeling of the ~60k tyrosine hydroxylase protein.