Oligodendrocyte Transcription Factor 1 (OLIG1) Antikörper

Antigen: Oligodendrocyte Transcription Factor 1 (OLIG1)

Synonyme: BHLHB6, BHLHE21, Olg-1, Bhlhb6, Oligo1, bHLHe21, AI836478, AW494459, Olg1, OLIG1

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Ratte (Rattus), Maus

Applikation: Western Blot (WB), Immunhistochemie (IHC), Immunzytochemie (ICC), Immunpräzipitation (IP)

Produktnummer: ABIN361358

Produktbeschreibung

Weitere Bezeichnung: Olig1

Beschreibung: Olig genes have been identified as the earliest known markers of oligodendrocyte lineage determination to date (Zhou et al., 2000). Olig1 is a transcription factor which promotes formation and maturation of oligodendrocytes, especially within the brain. It is expressed in the ventral spinal cord as early as 9.5 dpc and by 15.5 dpc, olig1 is dispersed throughout the gray matter. In the postnatal brain, it is present preferentially in the white matter, such as corpus callosum and cerebellar medulla. Olig1 has been demonstrated as necessary in the repair of brain lesions in patients with multiple sclerosis (Arnett et al. 2004). Anti-Olig1 Western blot of neonatal rat brain lysate showing specific immunolabeling of the ~ 27k Olig1 protein.

Spezifität: Specific for the ~27 kDa Olig1 protein in Western blots. The antibody also works well for immunohistochemistry, immunocytochemistry and immunoprecipitation.

Anwendungen

Applikationshinweise: Recommended Dilution: WB: 1:3,000 IHC & ICC: 1:1,000 IP: 1:50 Quality Control: Western blots performed on each lot.

Reinigung: Protein A purified rabbit serum.

Lagerung: Store at -20 °C, stable for 1 year

Forschungsgebiet: Neurologie, Glia Marker

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blots of neonatal rat brain lysate showing specific immunolabeling of the ~ 27k Olig1 protein.