Natural Cytotoxicity Triggering Receptor 1 (NCR1) Antikörper

Antigen: Natural Cytotoxicity Triggering Receptor 1 (NCR1)

Klonalität: Monoklonal (N1D9)

Wirt: Maus

Reaktivität: Human

Applikation: ELISA, Western Blot (WB), Durchflusszytometrie (FACS)

Produktnummer: ABIN361083

Produktbeschreibung

Weitere Bezeichnung: NKp46

Immunogen: Recombinant NKp46, Accession / GI number: NP_004820

Isotyp: TBD, kappa chain

Klon: N1D9

Beschreibung: A natural cytotoxicity receptor (NCR), NKp46, is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 residue stalk resion, a type I transmembrane domain, and a short cytoplasmic tail. NKp46 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NKp46 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.

Anwendungen

Konzentration: 1mg/ml

Reinigung: The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

Buffer: In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

Lagerung: Store at -20°, Aliquot to avoid repeated freezing and thawing.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-Natural Cytotoxicity Triggering Receptor 1 (NCR1) antibody