CKMT1B Antikörper (N-Term)

Produktnummer ABIN359153

Der Kaninchen Polyklonal anti-CKMT1B Antikörper wird verwendet zum Nachweis von CKMT1B in Proben von Human und Maus. Er wurde validiert für WB und EIA.

Kurzübersicht für CKMT1B Antikörper (N-Term) (ABIN359153)

Target: CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CKMT1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-CKMT1B Antikörper

Bindungsspezifität: AA 62-92, N-Term

Spezifität: This antibody recognizes Creatine kinase MT (CKMT1).

Aufreinigung: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62~92 amino acids from the N-terminal region of Human CKMT1. Genename: CKMT1B, CKMT1A

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu CKMT1B

Target: CKMT1B (Creatine Kinase, Mitochondrial 1B (CKMT1B))

Andere Bezeichnung: CKMT

Hintergrund: Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase.Synonyms: Acidic-type mitochondrial creatine kinase, CKMT1A, CKMT1B, Creatine kinase U, Mia-CK, U-MtCK, ubiquitous mitochondrial Creatine kinase

Gen-ID: 1159, 9606

UniProt: P12532