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Antikörper
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anti-Sclerostin (SOST) (Center) Antikörper
Sclerostin (SOST) (Center) Antikörper
| Antigen |
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| Synonyme |
VBCH, 5430411E23Rik, SOST, LOC100313724 |
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Epitope
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| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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Alternativen Enzyme Immunoassay (EIA), Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)
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| Produktnummer |
ABIN358752 |
| Menge |
0.1 mg (0.25 mg/ml) |
| Preis |
330,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Weitere Bezeichnung
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Sclerostin / SOST
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Gen-ID
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50964
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Swiss-Prot
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Q9BQB4
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Immunogen
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KLH conjugated synthetic peptide between 141~171 amino acids from the Center region ofHuman SOST.
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Kreuzreaktivität
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Human
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Isotyp
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Ig (Passende Sekundärantikörper)
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Beschreibung
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Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domainand sequence similarity to the DAN (differential screening-selected gene aberrative inneuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-functionmutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis,which causes progressive bone overgrowth. A deletion downstream of the sclerostin gene,which causes reduced sclerostin expression, is associated with a milder form of thedisorder called van Buchem disease.
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Spezifität
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This antibody recognizes SOST (Center). Species: Human. Others not tested.
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Applikationshinweise
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ELISA: 1/1,000. Western Blot: 1/50-1/100Immunohistochemistry: 1/10-1/50. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Konzentration
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0.25 mg/ml
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Reinigung
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Purified
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Buffer
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PBS with 0.09% (W/V) Sodium Azide
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Lagerung
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Sclerostin (SOST)", Typ "Antikörper" finden
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Wirte
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Kaninchen (25), Ratte (2)
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Reaktivitäten
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Human (25), Maus (22), Ratte (Rattus) (16)
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Applikationen
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Durchflusszytometrie (FACS) (18), Immunfluoreszenz (IF) (18), Western Blot (WB) (10), ELISA (5), Immunhistochemie (Paraffinschnitte) (IHC (p)) (5), Enzyme Immunoassay (EIA) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunhistochemie (IHC) (2), Immunpräzipitation (IP) (2), Immunoelectron Microscopy (IEM) (1)
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Konjugate
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitope
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N-Term (3), Center (1)
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