CRK (pSer41) Antikörper
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Epitope
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| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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| Produktnummer |
ABIN358272 |
| Menge |
0.1 mg (0.25 mg/ml) |
| Preis |
330,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Produktmerkmale
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Synonyms: Proto-oncogene C-crk, p38, Adapter molecule crk
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Gen-ID
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1398
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Swiss-Prot
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P46108
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Immunogen
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This antibody is generated from rabbits immunized with a KLH conjugated syntheticphosphopeptide corresponding to amino acid residues surrounding S41 of human CRK.
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Kreuzreaktivität
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Human
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Isotyp
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Ig (Passende Sekundärantikörper)
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Beschreibung
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CRK is a member of an adapter protein family that binds to severaltyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homologydomains) and is involved in several signaling pathways, recruiting cytoplasmic proteins inthe vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminalSH2 domain of this protein functions as a positive regulator of transformation whereas theC-terminal SH3 domain functions as a negative regulator of transformation.
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Spezifität
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This antibody detects CRK pSer41. Predicted to cross react with Mouse (100% Antigen Homology). Species: Human. Others not tested. Add. Information: Molecular weight: 22906 Da
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Applikationshinweise
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ELISA: 1/1,000. Dot Blot: 1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Konzentration
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0.25 mg/ml
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Reinigung
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Aff - Purified
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Buffer
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PBS with 0.09% (W/V) Sodium Azide as preservative.
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Lagerung
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: This product is for research use only. Not for use in diagnostic or therapeutic procedures.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "CRK", Typ "Antikörper" finden
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Wirte
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Kaninchen (13), Maus (6)
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Reaktivitäten
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Human (19), Maus (3), Ratte (Rattus) (3)
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Applikationen
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Western Blot (WB) (14), Enzyme Immunoassay (EIA) (5), Immunhistochemie (Paraffinschnitte) (IHC (p)) (4), Dot Blot (Dot) (3), ELISA (Detektionsantikörper) (3), Immunzytochemie (ICC) (2), Immunfluoreszenz (IF) (2), Immunpräzipitation (IP) (2), ELISA (1), Durchflusszytometrie (FACS) (1)
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Epitope
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pSer41 (1), pTyr221 (1)
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Alternativen 
