Ganglioside GD2 Antikörper

Antigen: Ganglioside GD2

Klonalität: Monoklonal (Cov11H3)

Wirt: Maus

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN346846

Produktbeschreibung

Immunogen: Ganglioside GD2

Format: Tissue culture supernatant

Isotyp: IgG3 kappa  (Passende Sekundärantikörper)

Klon: Cov11H3

Spezifität: Monoclonal antibody reacts specifically with GD2 ganglioside. Cross Reactivities: Does not cross react with others gangliosides

Anwendungen

Applikationshinweise: Optimal dilutions should be determined by the end user. The following are guidelines only: ELISA : 1/10 to 1/100. Western Blot : 1/5 to 1/50

Buffer: Lyophilized from 0,5 ml of tissue culture supernatant. Preservative: None.

Lagerung: Short term storage: +4°C. Long term storage: -20°C

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Zebda, Pedron, Rebbaa et al.: "Deficiency of ganglioside biosynthesis in metastatic human melanoma cells: relevance of CMP-NeuAc:LacCer alpha 2-3 sialyltransferase (GM3 synthase)." in: FEBS letters, Vol. 362, Issue 2, pp. 161-4, 1995 (PubMed).

Portoukalian, David, Gain et al.: "Shedding of GD2 ganglioside in patients with retinoblastoma." in: International journal of cancer. Journal international du cancer, Vol. 53, Issue 6, pp. 948-51, 1993 (PubMed).

Thomas, Buronfosse, Combaret et al.: "Gangliosides protect human melanoma cells from ionizing radiation-induced clonogenic cell death." in: Glycoconjugate journal, Vol. 13, Issue 3, pp. 377-84, 1997 (PubMed).

Cerato, Birkle, Portoukalian et al.: "Variable region gene segments of nine monoclonal antibodies specific to disialogangliosides (GD2, GD3) and their O-acetylated derivatives." in: Hybridoma, Vol. 16, Issue 4, pp. 307-16, 1997 (PubMed).