Ochratoxin A Antikörper

Antigen: Ochratoxin A

Klonalität: Polyklonal

Wirt: Kaninchen

Applikation: ELISA

Produktnummer: ABIN343805

Produktbeschreibung

Immunogen: ochratoxin A conjugated to BSA

Format: Lyophilized

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Ochratoxin A, a toxin produced by Aspergillus ochraceus and Penicillium verrucosum, is one of the most abundant food-contaminating mycotoxins in the world. Human exposure occurs mainly through consumption of improperly stored food products, particularly contaminated grain and pork products, as well as coffee, wine grapes and dried grapes. The toxin has been found in the tissues and organs of animals, including human blood and breast milk. Ochratoxin A can cause immunosuppression and immunotoxicity in animals. The toxin's immunosuppressant activity in animals may include depressed antibody responses, reduced size of immune organs (such as the thymus, spleen, and lymph nodes), changes in immune cell number and function, and altered cytokine production. Immunotoxicity probably results from cell death following apoptosis and necrosis, in combination with slow replacement of affected immune cells due to inhibition of protein synthesis. For research purposes only Structure of ochratoxin A

Spezifität: Reacts with ochratoxin A from Aspergillus ochraceus. Crossreaction with ochratoxin B - 2%

Anwendungen

Reinheit: polyclonal affinity purified on Protein A IgGs

Buffer: purified IgGs were dialysed against bidest. water and lyophilised

Lagerung: after dilution store at +4°C

Forschungsgebiet: Toxine

Beschränkungen: Nur für Forschungszwecke einsetzbar