SMARCA4 Antikörper (C-Term)

Produktnummer ABIN343708

Dieser Maus Monoklonal Antikörper detektiert spezifisch SMARCA4 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SMARCA4 Antikörper (C-Term) (ABIN343708)

Target: SMARCA4 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SMARCA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: BRG-01

Produktdetails anti-SMARCA4 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-BRG1 Purified

Kreuzreaktivität (Details): Human, Other not determined

Produktmerkmale: The antibody BRG-01 recognizes an epitope within C-terminal part of human Brg1, a 205 kDa catalytic subunit of SWI2/SNF2-family chromatin-remodeling complexes.

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Bacterially produced GST-fused protein representing 242 C-terminal amino acids of human Brg1.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Western blotting: Recommended dilution: 10 μg/mL, positive control: HEK293 cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu SMARCA4

Target: SMARCA4 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))

Andere Bezeichnung: BRG1

Hintergrund: SWI/SNF related, matrix associated, actin dependen,Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair and DNA replication. Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes including those involved in interferon and stress response, immune cells differentiation, neurogenesis, cell cycle etc. and is absolutely necessary for mouse embryogenesis. Brg1 is also involved in cell growth arrest, senescence and tumour supression.,CSS4, SMARCA4, SNF2, SWI2, MRD16, RTPS2, BAF190, SNF2L4, SNF2LB

Gen-ID: 6597

UniProt: P51532

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance