CCR6 Antikörper (AA 18-46)

Produktnummer ABIN337207

Dieser Ziege Polyklonal Antikörper detektiert spezifisch CCR6 in ELISA, FACS, IHC, IHC (p) und ICC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CCR6 Antikörper (AA 18-46) (ABIN337207)

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CCR6 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Produktdetails anti-CCR6 Antikörper

Bindungsspezifität: AA 18-46

Spezifität: Recognizes human CCR6. Peptide sequence is <50 % identical to other human chemokine receptors in this region. Species cross-reactivity: mouse.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey (86%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide corresponding to aa 18-46 (Y18FVSVNTSYYSVDSEMLLCSLQEVRQFSR46) of human CCR6 (C-C chemokine receptor 6). Peptide sequence is <50% identical to other human chemokine receptors in this region. Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%), Monkey (86%).

Type of Immunogen: Synthetic peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: ELISA (1:75000), Flo (1 - 3 μg/10 x10⁶), ICC (1:300), IHC, IHC-P (5 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. ELISA: 1:75000. Flow Cytometry: 50-100 μL, 1-3 μL per 10^6 cells.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 1 mg/mL BSA, 0.1 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu CCR6

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Andere Bezeichnung: CCR6

Hintergrund: Name/Gene ID: CCR6
Subfamily: Chemokine
Family: GPCR

Synonyms: CCR6, C-c chemokine receptor 6, CD196 antigen, BN-1, C-C chemokine receptor type 6, C-C CKR-6, Chemokine c-c motif receptor 6, CKRL3, CMKBR6, Chemokine (C-C) receptor 6, Chemokine receptor-like 3, Cc chemokine receptor 6, CC-CKR-6, CCR-6, DCR2, DRY6, G protein-coupled receptor 29, DRY-6, G-protein coupled receptor 29, GPR29, GPRCY4, Strl-22, STRL22, CD196, CKR-L3, GPR-CY4, LARC receptor

Gen-ID: 1235

UniProt: P51684

Pathways: cAMP Metabolic Process