NR1I2 Antikörper (Internal Region)

Produktnummer ABIN335159

Der Ziege Polyklonal anti-NR1I2 Antikörper wird verwendet zum Nachweis von NR1I2 in Proben von Human. Er wurde validiert für WB, IHC und ELISA.

Kurzübersicht für NR1I2 Antikörper (Internal Region) (ABIN335159)

Target: NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser NR1I2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Güteklasse: Verified

Produktdetails anti-NR1I2 Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: PXR / NR1I2

Sequenz: EQFAITLKSY IECNR

Spezifität: This antibody is expected to recognize all reported isoforms (NP_071285.1, NP_148934.1, NP_003880.3).

Kreuzreaktivität: Human

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence EQFAITLKSYIECNR, from the internal region of the protein sequence according to NP_003880.3, NP_071285.1, NP_148934.1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry: Paraffin embedded Human Small Intestine. Recommended concentration: 3.75 μg/mL.

Western Blot: Approx. 48 kDa band observed in lysates of cell line HepG2 (calculated MW of 49.8 kDa according to NP_003880.3). Recommended concentration: 1-3 μg/mL. An additional band of unknown identity was also consistently observed at 35 kDa. This band wa

Peptide ELISA: antibody detection limit dilution 1:4000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Details zu NR1I2

Target: NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))

Andere Bezeichnung: NR1I2

Hintergrund: PXR, NR1I2, nuclear receptor subfamily 1, group I, member 2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, SAR, SXR, orphan nuclear receptor, pregnane X receptor, steroid and xenobiotic receptor

Gen-ID: 8856

NCBI Accession: NP_003880, NP_071285, NP_148934

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway