TACR3 Antikörper (Middle Region)

Produktnummer ABIN318919

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TACR3 in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für TACR3 Antikörper (Middle Region) (ABIN318919)

Target: TACR3 (Tachykinin Receptor 3 (TACR3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TACR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TACR3 Antikörper

Bindungsspezifität: Middle Region

Spezifität: This antibody recognises TACR3 otherwise known as NK3 Receptor (NK3R), a 52.2 kDa multi-pass membrane protein belonging to the G-protein coupled receptor 1 family. This antibody does not recognise NK1R or NK2R.

Aufreinigung: Purified

Immunogen: An 18 amino acid peptide from near the centre of Human TACR3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on paraffin sections: 5g/mL, requires antigen retrieval using heattreatment prior to staining of paraffin sections. Western Blot: 0.5 - 1.0g/mL, detects a band of approximately 46 kDa in RAW264.7 celllysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu TACR3

Target: TACR3 (Tachykinin Receptor 3 (TACR3))

Hintergrund: TACR3 is a receptor for the tachykinin neuropeptide, neuromedin-k otherwise known as neurokinin B and is highly expressed in the supraoptic and paraventricular nuclei. Following binding of its ligand, NK3R activates a phosphatidylinositol-calcium second messenger system, and it is likely that these signals lead to the release of vasopressin and oxytocin into the circulation. Studies with mice indicate that TACR3 is involved in learning and memory.Synonyms: NK-3 receptor, NK-3R, NK3R, NKR, Neurokinin B receptor, Neuromedin-K receptor, TAC3R

Gen-ID: 6870

NCBI Accession: NP_001050

UniProt: P29371

Pathways: Feeding Behaviour