TAP1 Antikörper (C-Term)

Produktnummer ABIN318815

Der Kaninchen Polyklonal anti-TAP1 Antikörper wird verwendet zum Nachweis von TAP1 in Proben von Human. Er wurde validiert für WB, IP, FACS und EIA.

Kurzübersicht für TAP1 Antikörper (C-Term) (ABIN318815)

Target: TAP1 (Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Produktdetails anti-TAP1 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects an epitope within the C-terminal region of human TAP1, also known as transporter associated with antigen processing 1. This antibody does not cross react with TAP2.

Aufreinigung: Purified

Immunogen: TAP1 peptide corresponding to the C-terminal of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry. ELISA: 1: 10000. Immunoprecipitation. Western Blot: 1: 1000, detects a band of approximately 72 kDa.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline pH 7.2 containing 0.01 % Sodium Azide (NaN3)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu TAP1

Target: TAP1 (Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1))

Andere Bezeichnung: ABCB2 / APT1 / TAP1

Hintergrund: TAP1 is an 81kD membrane-associated protein which is a member of the ATP-binding cassette (ABC) transporter superfamily and together with the homologous subunit TAP2 forms the functional TAP complex. TAP1 is involved in the transport of antigenic peptides from the cytosol into the endoplasmic reticulum, where they associate with major histocompatibility complex (MHC) class I molecules. These complexes are presented at the cell surface to T-lymphocytes, which identify and remove infected or malignantly transformed cells.Synonyms: ATP-binding cassette sub-family B member 2, Antigen peptide transporter 1, PSF1, Peptide supply factor 1, Peptide transporter PSF1, Peptide transporter involved in antigen processing 1, RING4, Y3

Gen-ID: 6890

NCBI Accession: NP_000584

UniProt: Q03518

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response