Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antikörper

Antigen: Hepatitis A Virus Cellular Receptor 1 (HAVCR1)

Synonyme: KIM1, TIM1, HAVCR, KIM-1, TIM-1, TIMD1, HAVCR-1, Kim1, HAVCR1, LOC100226241

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN318766

Produktbeschreibung

Produktmerkmale: Synonyms: TIMD-1, TIM1, TIM-1, T cell membrane protein 1, HAVCR-1, T cell immunoglobulin and mucindomain-containing protein 1, Hepatitis A virus cellular receptor 1

Weitere Bezeichnung: TIMD1 / HAVCR1

Swiss-Prot: Q96D42

Immunogen: 16 amino acid peptide sequence near the centre of human TIM-1.

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: TIM-1 is a key cell surface protein that binds TIM-4, leading to T cell proliferation and Thelper type 2 (Th2) cytokine production. TIM-1 has also been shown to bind and activatemacrophages. Two splice variants for human TIM-1 exist, TIM-1a is predominantly expressed in the liver,whilst TIM-1b is expressed in the kidney. Expression of TIM-1 in the kidney is thought to beupregulated in damaged tissue, and is thought to assist healing. TIM-1 polymorphisms are associated with asthma.

Spezifität: This antibody detects T cell immunoglobulin mucin-1 (TIM-1), which was first identified asthe receptor used by hepatitis A for viral entry (it is also known as the hepatitis A viruscellular receptor- HAVCR). Species: Human, Mouse, Rat. Others not tested.

Anwendungen

Applikationshinweise: Western Blot: 1.0 - 2.0g/ml, detects a band of approximately 49kDa in human uterustissue lysate. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Konzentration: 1.0mg/ml

Reinigung: Purified

Buffer: Phosphate buffered saline containing 0.02% Sodium Azide

Lagerung: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.

Beschränkungen: Nur für Forschungszwecke einsetzbar