HAVCR1 Antikörper (Middle Region)
Kurzübersicht für HAVCR1 Antikörper (Middle Region) (ABIN318765)
Target
Alle HAVCR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- Middle Region
-
Spezifität
- This antibody detects T cell immunoglobulin mucin-1 (TIM-1), which was first identified as the receptor used by hepatitis A for viral entry (it is also known as the hepatitis A virus cellular receptor- HAVCR).
-
Aufreinigung
- Purified
-
Immunogen
- 16 amino acid peptide sequence near the centre of human TIM-1.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
Western Blot: 1.0 - 2.0g/mL, detects a band of approximately 49 kDa in human uterustissue lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1.0 mg/mL
-
Buffer
- Phosphate buffered saline containing 0.02 % Sodium Azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freezing and thawing.
-
Lagerung
- 4 °C/-20 °C
-
Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))
-
Andere Bezeichnung
- TIMD1 / HAVCR1
-
Substanzklasse
- Virus
-
Hintergrund
- TIM-1 is a key cell surface protein that binds TIM-4, leading to T cell proliferation and T helper type 2 (Th2) cytokine production. TIM-1 has also been shown to bind and activate macrophages. Two splice variants for human TIM-1 exist, TIM-1a is predominantly expressed in the liver, whilst TIM-1b is expressed in the kidney. Expression of TIM-1 in the kidney is thought to be upregulated in damaged tissue, and is thought to assist healing. TIM-1 polymorphisms are associated with asthma.Synonyms: HAVCR-1, Hepatitis A virus cellular receptor 1, T cell immunoglobulin and mucin domain-containing protein 1, T cell membrane protein 1, TIM-1, TIM1, TIMD-1
-
Gen-ID
- 26762
-
NCBI Accession
- NP_001092884
-
UniProt
- Q96D42
Target
-