NDRG4 Antikörper

Produktnummer ABIN317933

Der Kaninchen Polyklonal anti-NDRG4 Antikörper wird verwendet zum Nachweis von NDRG4 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und IHC (p).

Kurzübersicht für NDRG4 Antikörper (ABIN317933)

Target: NDRG4 (NDRG Family Member 4 (NDRG4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDRG4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-NDRG4 Antikörper

Spezifität: NDRG4 antibody detects endogenous levels of NDRG4 protein. (region surrounding Gly217)

Aufreinigung: Affinity chromatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu NDRG4

Target: NDRG4 (NDRG Family Member 4 (NDRG4))

Andere Bezeichnung: NDRG4

Hintergrund: The N-Myc downstream regulated gene (NDRG) family is comprised of four members, namely NDRG1, NDRG2, NDRG3 and NDRG4, all of which share 57-65 % homology. NDRG4 (NDRG family member 4), also known as SMAP8 (smooth muscle-associated protein 8) or BDM1 (brain development-related molecule 1), is a 352 amino acid cytoplasmic protein that belongs to the NDRG family. Expressed specifically in brain and heart, NDRG4 is thought to function as a regulator of mitogenic signaling in vascular smooth muscle cells. Additionally, NDRG4 may play a role in early postnatal development and may mediate the differentiation and subsequent function of neuronal cells. NDRG4 is expressed as six isoforms (the first three of which are designated NDRG4- BVar, NDRG4-B and NDRG4-H) due to alternative splicing events.Synonyms: BDM1, Brain development-related molecule 1, KIAA1180

Molekulargewicht: approx. 34 kDa

Gen-ID: 65009

NCBI Accession: NP_001123959

UniProt: Q9ULP0