GNGT1 Antikörper

Produktnummer ABIN317913

Der Kaninchen Polyklonal anti-GNGT1 Antikörper (ABIN317913) detektiert spezifisch GNGT1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für GNGT1 Antikörper (ABIN317913)

Target: GNGT1 (G Protein gamma Transducing Activity Polypeptide 1 (GNGT1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNGT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GNGT1 Antikörper

Spezifität: Gα t1 antibody detects endogenous levels of Gα t1 protein.(region surrounding Met104)

Aufreinigung: Affinity chromatography

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GNGT1

Target: GNGT1 (G Protein gamma Transducing Activity Polypeptide 1 (GNGT1))

Andere Bezeichnung: G Protein gamma T1

Hintergrund: Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e. adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein α, β and γ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their α subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of Gα subunits have been identified, these include Gs, Gi, Gq and Gα 12/13. The Gi class comprises all the known α subunits that are susceptible to pertussis toxin modifications, including Gα i-1, Gα i-2, Gα i-3, Gα o, Gα t1, Gα t2, Gα z and Gα gust. In the well characterized visual system, photorhodopsin catalyzes the exchange of guanine nucleotides bound to the visual transducin Gα subunits (Gα t1 in rod cells and Gα t2 in cone cells).Synonyms: GNGT1, Guanine nucleotide-binding protein G T subunit gamma-T1, Transducin gamma chain

Molekulargewicht: approx. 36 kDa

Gen-ID: 2792

NCBI Accession: NP_068774

UniProt: P63211

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction