ADAM Metallopeptidase Domain 2 (ADAM2) Antikörper

Antigen: ADAM Metallopeptidase Domain 2 (ADAM2)

Synonyme: CT15, FTNB, PH30, CRYN1, CRYN2, PH-30b

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB)

Produktnummer: ABIN311594

Produktbeschreibung

Weitere Bezeichnung: ADAM2 / FTNB

Beschreibung: ADAM2 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM2 is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions.This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Keywords: ADAM2, NM_001464, NP_001455, Q99965

Anwendungen

Applikationshinweise: ELISA titre: 1:312500 . Western Blotting: Suggested dilution at 1 u ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-ADAM Metallopeptidase Domain 2 (ADAM2) antibody

Publikationen

Publikationen: Eto, Huet, Tarui et al.: "Functional classification of ADAMs based on a conserved motif for binding to integrin alpha 9beta 1: implications for sperm-egg binding and other cell interactions." in: The Journal of biological chemistry, Vol. 277, Issue 20, pp. 17804-10, 2002 (PubMed).