SF3A3 Antikörper (Middle Region)

Produktnummer ABIN310069

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SF3A3 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen und Saccharomyces cerevisiae.Es wurde in 1 Publikation zitiert.

Kurzübersicht für SF3A3 Antikörper (Middle Region) (ABIN310069)

Target: SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SF3A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SF3A3 Antikörper

Bindungsspezifität: Middle Region

Sequenz: THENVQRKQA RTGEEREEEE EEQISESESE DEENEIIYNP KNLPLGWDGK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against SF3A3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SF3A3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 501 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SF3A3 Antikörper (ABIN310069)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Details zu SF3A3

Target: SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))

Andere Bezeichnung: SF3A3

Hintergrund: SF3A3 is the subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP.This This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PRP9, PRPF9, SAP61, SF3a60
Protein Interaction Partner: TRIM69, HUWE1, ZNF212, TADA2A, FUS, UBC, NEDD8, MDM2, WWOX, RNF2, SUZ12, EED, rev, APBB1, ACTN1, ACTN4, STAM2, HGS, SNRPB, CDAN1, PRPF40A, WBP4, TCERG1, UBD, SF3A1, FN1, gag-pol, PRMT5, PRPF19, PRPF31, SF3B1, SF3B3, SF3B4, HNRNPR, DDX46, TOX4, DDX23, PRPF
Protein Size: 501

Molekulargewicht: 59 kDa

Gen-ID: 10946

NCBI Accession: NM_006802, NP_006793

UniProt: Q12874

Pathways: Ribonucleoprotein Complex Subunit Organization