SRY (Sex Determining Region Y)-Box 2 (SOX2) Antikörper

Antigen: SRY (Sex Determining Region Y)-Box 2 (SOX2)

Synonyme: ANOP3, MCOPS3, MGC2413, RGD1565646, SOX2, MGC148683, lcc, ysb, Sox-2

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Hund, Huhn, Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN309867

Produktbeschreibung

Weitere Bezeichnung: SOX2

Beschreibung: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation.This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Keywords: SOX2 (SRY (sex determining region Y)-box 2) Antibody, NM_003106, NP_003097, P48431, NM_004189, NP_004180, O95416, NM_005986, NP_005977, O00570, NM_007084, NP_009015, Q9Y651

Anwendungen

Applikationshinweise: ELISA titre: 1:1562500 . Western Blotting: Suggested dilution at 2.5 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.

Forschungsgebiet: Embryogenese, Embryonale Stammzellen, Reproduktion, Transkriptionsfaktoren, Neuronale Stammzellmarker

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-SRY (Sex Determining Region Y)-Box 2 (SOX2) antibody

Publikationen

Publikationen: Lei, Liu, Sodja et al.: "S/MAR-binding properties of Sox2 and its involvement in apoptosis of human NT2 neural precursors." in: Cell death and differentiation, Vol. 12, Issue 11, pp. 1368-77, 2005 (PubMed).