AKAP7 Antikörper (Middle Region)
Kurzübersicht für AKAP7 Antikörper (Middle Region) (ABIN309820)
Target
Alle AKAP7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- MKLSKSPWLR KNGVKKIDPD LYEKFISHRF GEEILYRIDL CSMLKKKQSN
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Homologie
- Cow: 83%, Dog: 91%, Horse: 92%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against AKAP7. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human AKAP7
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 326 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- AKAP7 (A Kinase (PRKA) Anchor Protein 7 (AKAP7))
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Andere Bezeichnung
- AKAP7
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Hintergrund
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AKAP7 is a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined.This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined.
Alias Symbols: AKAP18, AKAP15
Protein Interaction Partner: CEP76, ROPN1, SPA17, PRKAR2B, PRKACB, PRKACA, MEPCE, USP4, PRKAR1A, PRKAR2A,
Protein Size: 326 -
Molekulargewicht
- 37 kDa
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Gen-ID
- 9465
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NCBI Accession
- NM_016377, NP_057461
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UniProt
- Q9P0M2
Target
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