Acyl-CoA Dehydrogenase, Long Chain (ACADL) Antikörper

Antigen: Acyl-CoA Dehydrogenase, Long Chain (ACADL)

Synonyme: LCAD, ACAD4, FLJ94052, ACOADA, MGC55656, zgc:55656, ACADL, acadl, MGC83156, MGC151674

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Rind (Kuh), Human, Maus, Schwein, Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN309715

Produktbeschreibung

Weitere Bezeichnung: ACADL

Beschreibung: ACADL belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in ACADL gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. Keywords: ACADL, NM_001608, NP_001599, P28330

Anwendungen

Applikationshinweise: ELISA titre: 1:12500 . Western Blotting: Suggested dilution at 0.25 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as second antibody.

Forschungsgebiet: Krebs, Fettsäuren, Metabolismus

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

anti-Acyl-CoA Dehydrogenase, Long Chain (ACADL) antibody

Publikationen

Publikationen: Lea, Abbas, Sprecher et al.: "Long-chain acyl-CoA dehydrogenase is a key enzyme in the mitochondrial beta-oxidation of unsaturated fatty acids." in: Biochimica et biophysica acta, Vol. 1485, Issue 02. Mrz, pp. 121-8, 2000 (PubMed).