NR1I3 Antikörper (C-Term)

Produktnummer ABIN309705

Der Kaninchen Polyklonal anti-NR1I3 Antikörper (ABIN309705) detektiert spezifisch NR1I3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Schwein, Pferd und Kaninchen.

Kurzübersicht für NR1I3 Antikörper (C-Term) (ABIN309705)

Target: NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Schwein, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR1I3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NR1I3 Antikörper

Bindungsspezifität: C-Term

Sequenz: FHGTLRKLQL QEPEYVLLAA MALFSPDRPG VTQRDEIDQL QEEMALTLQS

Homologie: Cow: 77%, Dog: 77%, Guinea Pig: 85%, Horse: 75%, Human: 100%, Mouse: 92%, Pig: 92%, Rabbit: 92%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against NR1I3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NR1I3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 348 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NR1I3

Target: NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))

Andere Bezeichnung: NR1I3

Hintergrund: NR1I3 is a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members.
Alias Symbols: CAR, CAR-BETA, CAR-SV1, CAR-SV10, CAR-SV11, CAR-SV12, CAR-SV13, CAR-SV14, CAR-SV15, CAR-SV17, CAR-SV18, CAR-SV19, CAR-SV20, CAR-SV21, CAR-SV4, CAR-SV6, CAR-SV7, CAR-SV8, CAR-SV9, CAR1, MB67, MGC97144
Protein Interaction Partner: HSP90AA1, RXRA, CHD9, SNX13, SNRPD3, IGH, PSMC5, PSMC4, EIF3I, SRC, MAP4, FTH1, HNF4A, NR0B2, PPARGC1A, MED1, NCOA1, POU1F1,
Protein Size: 348

Molekulargewicht: 40 kDa

Gen-ID: 9970

NCBI Accession: NM_005122, NP_005113

UniProt: Q5VTW5

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway