PCSK6 Antikörper (Internal Region)

Produktnummer ABIN308447

Es gibt 1 Publikation für dieses Produkt. Der Ziege Polyklonal anti-PCSK6 Antikörper wird verwendet zum Nachweis von PCSK6 in Proben von Human. Er wurde validiert für ELISA und IHC.

Kurzübersicht für PCSK6 Antikörper (Internal Region) (ABIN308447)

Target: PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser PCSK6 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Güteklasse: Verified

Produktdetails anti-PCSK6 Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: PACE4

Sequenz: PDCEPGTYFD SE

Spezifität: This antibody is expected to recognize reported isoforms a, b, g, h (NP_002561.1, NP_612192.1, NP_612193.1, NP_612194.1 resp.).

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence PDCEPGTYFDSE, from the internal region of the protein sequence according to NP_002561.1, NP_612192.1, NP_612195.1, NP_612197.1, NP_612196.1, NP_612198.2, NP_612193.1, NP_612194.1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry: Paraffin embedded Human Testis and Skeletal Muscle. Recommended concentration: 3.75 μg/mL.

Western Blot: Preliminary experiments gave an approx. 70 kDa band in Human, Mouse and Rat Liver lysates after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated

Peptide ELISA: antibody detection limit dilution 1:8000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Referenzen für anti-PCSK6 Antikörper (ABIN308447)

Ha, Jin, Jorgensen, Zogg, Wei, Singh, Park, Kurahashi, Kim, Baek, Poudrier, Lee, Sanders, Ro: "Transcriptome profiling of subepithelial PDGFRα cells in colonic mucosa reveals several cell-selective markers." in: PloS one, Vol. 17, Issue 5, pp. e0261743, (2022) (PubMed).

Details zu PCSK6

Target: PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))

Andere Bezeichnung: PCSK6

Hintergrund: PCSK6, proprotein convertase subtilisin/kexin type 6, PACE4, SPC4, paired basic amino acid cleaving system 4, subtilisin-like proprotein convertase 4, subtilisin-like protease, subtilisin/kexin-like protease PACE4

Gen-ID: 5046, 18553, 25507

NCBI Accession: NP_002561, NP_612192, NP_612195, NP_612197, NP_612196, NP_612198, NP_612193, NP_612194

Pathways: Neurotrophin Signalübertragung, SARS-CoV-2 Protein Interaktom