Voltage-gated Calcium Channel Subunit alpha-2/delta-1 (CACNA2D1) Antikörper

Antigen: Voltage-gated Calcium Channel Subunit alpha-2/delta-1 (CACNA2D1)

Synonyme: CCHLA2, Cacna2, DHSCCA

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN306883

Produktbeschreibung

Weitere Bezeichnung: L-type calcium channel alpha2/delta subunit

Swiss-Prot: Q8VHS9

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: The calcium channel alpha2/delta subunit is a glycosylated structural subunit consisting of the alpha2 subunit and the delta peptide. There is distinctive alpha2 subunit expression in rat spinal cord and dorsal root ganglia (DRG) There are two forms of the alpha2 subunit in DRG that are different from the alpha2 subunit in other tissues examined, at least at the glycosylation level. Thus, post-translational modification may be important in tissue specific and functional expression of the alpha2/delta subunit (2). alpha2/delta and beta1b interact with alpha1G to increase trafficking of, or stabilize, functional alpha1G channels expressed at the plasma membrane.(3)

Anwendungen

Applikationshinweise: This antibody can be used for Western blotting (5-10 ug/ml). Positive Control: Rat brain lysate.

Konzentration: 1 mg/ml

Lagerung: Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles

Beschränkungen: Nur für Forschungszwecke einsetzbar