SH3 Binding Protein 2 (3BP2) Antikörper

Antigen: SH3 Binding Protein 2 (3BP2)

Synonyme: 3BP2

Klonalität: Polyklonal

Wirt: Schaf

Reaktivität: Maus

Applikation: Western Blot (WB)

Produktnummer: ABIN306729

Produktbeschreibung

Weitere Bezeichnung: 3BP2 (SH3 Binding Protein 2)

Swiss-Prot: Q06649

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: 3BP2 (SH3 binding protein 2) was identified as a protein binding to the SH3 domain of the Abl proto-oncogene. Murine 3BP2 cDNA encodes a 559 amino acid protein of 85 kDa consisting of an N-terminal PH domain, a C-terminal SH2 domain and intervening proline-rich sequences. 3BP2 interacts via its Sh2 domain with Syk family protein tyrosine kinases Syk, Zap70, Grb2, Cbl, PLC 1 and LAT in T lymphocytes and contributes to the transcriptional activation of NF-AT and AP-1. Mouse 3BP2 is 66% homologous to the human protein at the amino acid level. Synonyms: Sh3bp2, SH3 domain-binding protein 2.

Anwendungen

Applikationshinweise: Detects 3BP2 protein by Western blot analysis. Detects a 85 kDa band in murine fibroblasts transfected with 3BP2. Positive Control: Recombinant 3BP2 protein.

Konzentration: 1 mg/ml

Lagerung: Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles

Beschränkungen: Nur für Forschungszwecke einsetzbar