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SH3 Binding Protein 2 (3BP2) Antikörper
| Antigen | SH3 Binding Protein 2 (3BP2) |
| Synonyme | 3BP2 |
| Klonalität | Polyklonal |
| Wirt |
Schaf |
| Reaktivität |
Maus |
| Applikation |
Western Blot (WB)
|
| Produktnummer | ABIN306729 |
| Menge | 250 ug (1 mg/ml) |
| Preis | 244,10 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
|
| Verfügbarkeit | Lieferung in 5 bis 7 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | 3BP2 (SH3 Binding Protein 2) |
| Swiss-Prot | Q06649 |
| Isotyp | IgG (Passende Sekundärantikörper) |
| Beschreibung | 3BP2 (SH3 binding protein 2) was identified as a protein binding to the SH3 domain of the Abl proto-oncogene. Murine 3BP2 cDNA encodes a 559 amino acid protein of 85 kDa consisting of an N-terminal PH domain, a C-terminal SH2 domain and intervening proline-rich sequences. 3BP2 interacts via its Sh2 domain with Syk family protein tyrosine kinases Syk, Zap70, Grb2, Cbl, PLC 1 and LAT in T lymphocytes and contributes to the transcriptional activation of NF-AT and AP-1. Mouse 3BP2 is 66% homologous to the human protein at the amino acid level. Synonyms: Sh3bp2, SH3 domain-binding protein 2. |
Anwendungen
| Applikationshinweise | Detects 3BP2 protein by Western blot analysis. Detects a 85 kDa band in murine fibroblasts transfected with 3BP2. Positive Control: Recombinant 3BP2 protein. |
| Konzentration | 1 mg/ml |
| Lagerung | Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
