TAP1 Antikörper (C-Term)

Produktnummer ABIN305531

Der Kaninchen Polyklonal anti-TAP1 Antikörper wird verwendet zum Nachweis von TAP1 in Proben von Human. Er wurde validiert für WB, ELISA, IP und FACS.

Kurzübersicht für TAP1 Antikörper (C-Term) (ABIN305531)

Target: TAP1 (Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS)

Produktdetails anti-TAP1 Antikörper

Bindungsspezifität: C-Term

Spezifität: Detects an epitope within the C-terminal region of human TAP1, also known as transporter associated with antigen processing 1. TAP1 is an 81kD membrane-associated protein which is a member of the ATP-binding cassette (ABC) transporter superfamily and together with the homologous subunit TAP2 forms the functional TAP complex. TAP1 is involved in the transport of antigenic peptides from the cytosol into the endoplasmic reticulum, where they associate with major histocompatibility complex (MHC) class I molecules. These complexes are presented at the cell surface to T-lymphocytes, which identify and remove infected or malignantly transformed cells. AHP1248 does not cross react with TAP2.

Aufreinigung: Purified IgG

Immunogen: TAP1 peptide corresponding to the C-terminal of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH). ( C-TERMINAL ).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: ELISA (1:10000), Flo, IP, WB (1:1000)

Usage: Western Blot: LS-C42564 detects a band of approximately 72kD.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.2, 0.01 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze thaw cycles. Store undiluted.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.

Details zu TAP1

Target: TAP1 (Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1))

Andere Bezeichnung: ABCB2 / TAP1

Hintergrund: Name/Gene ID: TAP1
Subfamily: ATP-binding cassette - ABCB/MDR
Family: Transporter

Synonyms: TAP1, ABC17, ABCB2, APT1, D6S114E, ABC transporter, MHC 1, Ham1, Peptide transporter TAP1, PSF1, TAP1N, MTP1, Peptide transporter PSF1, PSF-1, Peptide supply factor 1, RING4, Y3

Gen-ID: 6890

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response