Fibrinogen (Fbg) Antikörper

Antigen: Fibrinogen (Fbg)

Synonyme: fib2, MGC53620, fibrinogen, Fib, ENSMUSG00000059807, Fba5e, Ac1873, MGC156536, sb:cb892, zgc:92117, wu:fa55c12, wu:fi39d04, FGA, MGC128011

Klonalität: Monoklonal (40F11)

Wirt: Maus

Reaktivität: Human

Applikation: Western Blot (WB), ELISA

Produktnummer: ABIN305095

Produktbeschreibung

Weitere Bezeichnung: Fibrinogen

Immunogen: Fibrin degradation products.

Isotyp: IgG1  (Passende Sekundärantikörper)

Klon: 40F11

Beschreibung: Gene: Fibrinogen

Spezifität: Recognizes human fibrinogen, a glycoprotein produced in the liver. Fibrinogen is a hexamer, consisting of two sets of three subunits (alpha, beta and gamma). Thrombin converts fibrinogen into fibrin, which is then cross-linked by factor XIII to form a blood clot. Recognizes fibrin degradation products (FDPs), substances that are left behind after a blood clot dissolves. This process, called fibrinolysis, is produced by the action of enzymes such as plasmin on fibrin. One FDP is D-dimer, levels of which can be used to diagnose deep vein thrombosis or pulmonary embolism. The fibrinolytic system is also closely linked to the control of inflammation. May be used to detect fibrinogen in ELISA assays

Anwendungen

Applikationshinweise: ELISA, WB

Reinigung: Affinity Chromatography

Buffer: PBS, pH 7.4, 0.09% sodium azide.

Lagerung: Long term: -20°C, Short term: -20°C

Forschungsgebiet: Kardiovaskuläres System, Artherosklerose, Extrazelluläre Matrix, Gerinnung

Beschränkungen: Nur für Forschungszwecke einsetzbar