Ectodysplasin A2 Receptor Antikörper

Produktnummer ABIN303257

Der Kaninchen Polyklonal anti-Ectodysplasin A2 Receptor Antikörper wird verwendet zum Nachweis von Ectodysplasin A2 Receptor in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für Ectodysplasin A2 Receptor Antikörper (ABIN303257)

Target: Ectodysplasin A2 Receptor (EDA2R)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ectodysplasin A2 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Ectodysplasin A2 Receptor Antikörper

Spezifität: This antibody reacts to Human EDA2R, antibody does not detect mouse EDA2R.

Aufreinigung: Purified

Immunogen: Recombinant human EDA2R

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections (2.5 μg/mL). Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Ectodysplasin A2 Receptor

Target: Ectodysplasin A2 Receptor (EDA2R)

Andere Bezeichnung: EDA2R / TNFRSF27

Hintergrund: EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support.Synonyms: EDA-A2 receptor, Tumor necrosis factor receptor superfamily member 27, UNQ2448/PRO5727/PRO34080, X-linked ectodysplasin-A2 receptor, XEDAR

Gen-ID: 60401

NCBI Accession: NP_001186616

UniProt: Q9HAV5