TRPV2 Antikörper (N-Term)

Produktnummer ABIN302577

Der Kaninchen Polyklonal anti-TRPV2 Antikörper (ABIN302577) detektiert spezifisch TRPV2 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für TRPV2 Antikörper (N-Term) (ABIN302577)

Target: TRPV2 (Transient Receptor Potential Cation Channel, Subfamily V, Member 2 (TRPV2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRPV2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TRPV2 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects Transient Receptor Potential Cation Channel, Subfamily V, Member 2 (Trpv2) at N-terminal. (Family: Ion channel, Subfamily: Calcium channel - TRP).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: TRPV2 antibody was raised against synthetic peptide from N-terminal domain of human TRPV2. Genename: TRPV2

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections (10 μg/mL). Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.8 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer.

Details zu TRPV2

Target: TRPV2 (Transient Receptor Potential Cation Channel, Subfamily V, Member 2 (TRPV2))

Andere Bezeichnung: TRPV2 / VRL1

Hintergrund: Transient receptor potential vanilloid (TRPV) channels are widely expressed in both sensory and nonsensory cells. TRPV2, a member of transient receptor potential ion channels, responds to high-threshold noxious heat (with a threshold of approximately 52 degrees C), but neither to capsaicin nor to proton. TRPV2 transcripts are not restricted to the sensory nervous system, indicating that this channel may be activated by stimuli other than heat. It has been proposed that responses to noxious heat involve these related, but distinct, ion-channel subtypes that together detect a range of stimulus intensities.Synonyms: OTRPC2, Osm-9-like TRP channel 2, Transient receptor potential cation channel subfamily V member 2, VRL, VRL-1, Vanilloid receptor-like protein 1

Gen-ID: 51393

NCBI Accession: NP_057197

UniProt: Q9Y5S1

Pathways: Regulation of Cell Size