HLA-A2 Antikörper

Antigen: HLA-A2

Klonalität: Monoklonal (BB7-2)

Wirt: Maus

Reaktivität: Human

Applikation: Durchflusszytometrie (FACS), Immunpräzipitation (IP)

Produktnummer: ABIN301995

Produktbeschreibung

Immunogen: HLA-A2 solubilised by papain

Format: Azide Free

Isotyp: IgG2b  (Passende Sekundärantikörper)

Klon: BB7-2

Beschreibung: HLA-A2 (44 kDa) is the most frequent HLA-A allele in human ethnic populations. HLA-A,together with HLA-B and HLA-C, represent human HLA class I major histocompatibility(MHC) antigens. These intrinsic membrane glycoproteins are expressed on nucleated cellsand noncovalently associate with an invariant beta2 microglobulin. They carry foreigndeterminants important for immune recognition by cytotoxic T cells, thus important foranti-viral and anti-tumour defence.

Spezifität: The antibody BB7.2 recognizes an epitope at the C-terminus of alpha-2 helix and a turn onone of the underlying beta strands within the human HLA-A2 histocompatibility antigen.

Anwendungen

Konzentration: 1 mg/ml

Reinheit: > 95% (by SDS-PAGE)

Reinigung: Purified from ascites by protein-A affinity chromatography.

Buffer: Azide free phosphate buffered saline (PBS), approx. pH 7.4, 0.2 µ m filter sterilized.

Lagerung: Store at 2-8 o C. Do not use after expiration date stamped on vial label. For long-term storage aliquot and store at -20 o C. Avoid freeze/thaw cycles.

Forschungsgebiet: Haupthistokompatibilitätskomplex (MHC)

Beschränkungen: Nur für Forschungszwecke einsetzbar