ELISA: 0.5-1 µg/mL, IHC: 2-10 µg/mL, WB: 1-10 µg/mL Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Reconstitute in PBS to a concentration of 1 mg/mL.
Konzentration
Lot specific
Buffer
Lyophilized from PBS with 0.1 % BSA.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
Target
SLC6A3
(Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))
Andere Bezeichnung
Dopamine Transporter
Hintergrund
The dopamine transporter (also known as dopamine active transporter, DAT, SLC6A3) is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synapse back into cytosol, from which other transporters sequester DA and NE into vesicles for later storage and release. Dopamine reuptake via DAT provides the primary mechanism through which dopamine is cleared from synapses except in the prefrontal cortex, where dopamine uptake via the norepinephrine transporter plays that role.