»
Antikörper
»
anti-Cardiac Troponin I (TNNI3) Antikörper
Cardiac Troponin I (TNNI3) Antikörper
| Antigen |
|
| Synonyme |
CMH7, RCM1, cTnI, CMD2A, TNNC1, MGC116817, Tn1, LOC397803, TnIc, ctnIc, cmh7, ctni, tnnc1, TNNI3 |
| Klonalität |
Monoklonal (C5) |
|
Wirt
|
|
|
Reaktivität
|
Human (113), Rind (Kuh) (44), Kaninchen (18), Hund (17), Maus (16), Ratte (Rattus) (16), Schwein (12), Katze (11), Ziege (11), Huhn (5), Fisch (3), Säugetiere (2), Amphibien (1), Frosch (1), Affe (1)
|
|
Applikation
|
Western Blot (WB) (130), Enzyme Immunoassay (EIA) (104), Immunpräzipitation (IP) (82), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (75), ELISA (Detektionsantikörper) (9), Immunhistochemie (Paraffinschnitte) (IHC (p)) (9), ELISA (Fangantikörper) (5), ELISA (4), Immunhistochemie (IHC) (2), Radioimmunoassay (RIA) (2), Immunfluoreszenz (IF) (1)
|
| Produktnummer |
ABIN272322 |
| Menge |
1 mg (3.5mg/ml (Sigma protein assay kit)) (Varianten) |
| Preis |
430,00 € Zzgl. Versandkosten €20,00 und MWSt
|
| Lieferung nach |
|
| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
|
Produktmerkmale
|
Synonyms: TNNI3, TNNC1
|
|
Weitere Bezeichnung
|
Cardiac Troponin I (+ skeletal)
|
|
Swiss-Prot
|
P19429
|
|
Immunogen
|
Free human cardiac troponin I
|
|
Kreuzreaktivität
|
Amphibien, Rind (Kuh), Huhn, Fisch, Human, Maus, Kaninchen
|
|
Isotyp
|
IgG2b (Passende Sekundärantikörper)
|
|
Klon
|
C5
|
|
Beschreibung
|
Troponin I is part of a heteromeric complex playing an important role in the regulation ofskeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI),troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponincomplex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present incardiac muscles in different forms than in skeletal muscles. Only one tissue specificisoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only inmyocardium.
|
|
Spezifität
|
This antibody reacts equally with free cardiac Troponin I (cTnI) and cTnI forming complexeswith other troponin components. Not affected by heparin, phosphorylation and oxidation. Recognizes an epitope located between amino acid residues 186 and 192 of cTnI. Cross-reacts with skeletal troponin I from human, rat and mouse. Species: Human, Rat, Mouse, Chicken, Bovine, Fish, Rabbit, Amphibian. Others not tested.
|
|
Konzentration
|
3.5mg/ml (Sigma protein assay kit)
|
|
Reinigung
|
Purified
|
|
Buffer
|
PBS, pH 7.4 containing 0,09% sodium azide
|
|
Lagerung
|
Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
|
|
Forschungsgebiet
|
Serum/Plasma Proteine
|
|
Beschränkungen
|
Nur für Forschungszwecke einsetzbar
|
Alternativen zu Antigen "Cardiac Troponin I (TNNI3)", Typ "Antikörper" finden
|
Wirte
|
Maus (130), Kaninchen (12), Ziege (8), Huhn (1)
|
|
Reaktivitäten
|
Human (113), Rind (Kuh) (44), Kaninchen (18), Hund (17), Maus (16), Ratte (Rattus) (16), Schwein (12), Katze (11), Ziege (11), Huhn (5), Fisch (3), Säugetiere (2), Amphibien (1), Frosch (1), Affe (1)
|
|
Applikationen
|
Western Blot (WB) (130), Enzyme Immunoassay (EIA) (104), Immunpräzipitation (IP) (82), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (75), ELISA (Detektionsantikörper) (9), Immunhistochemie (Paraffinschnitte) (IHC (p)) (9), ELISA (Fangantikörper) (5), ELISA (4), Immunhistochemie (IHC) (2), Radioimmunoassay (RIA) (2), Immunfluoreszenz (IF) (1)
|
|
Epitope
|
AA 1-23 (1), AA 117-126 (1), AA 143-152 (1), AA 148-158 (1), AA 27-39 (1), AA 39-180 (1), AA 65-74 (1), AA 69-86 (1), AA 8-35 (1)
|
Alternativen 
