S1PR4 Antikörper (N-Term)

Produktnummer ABIN265061

Der Kaninchen Polyklonal anti-S1PR4 Antikörper wird verwendet zum Nachweis von S1PR4 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für S1PR4 Antikörper (N-Term) (ABIN265061)

Target: S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S1PR4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-S1PR4 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to EDG-6 / S1P4 / S1PR4.

Aufreinigung: Purified

Immunogen: Synthetic peptide derived from the N terminal of the EDG6 (S1P4) receptor

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 5 - 10 μg/mL, Detects an approximately 45 kDa band in Cos cells transfectedwith full length human EDG6 (S1P4) . Due to low expression of EDG receptors, werecommend use of Pierce Femto Signal substrate for western blot development.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu S1PR4

Target: S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))

Andere Bezeichnung: S1PR4 / EDG6

Hintergrund: EDG6 (S1P4) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG6 (S1P4) is sphingosine 1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG6 (S1P4) is expressed in lymphoid and hematopoietic tissue and in the lungs.Synonyms: EDG-6, Endothelial differentiation G-protein coupled receptor 6, S1P receptor Edg-6, Sphingosine 1-phosphate receptor 4, Sphingosine 1-phosphate receptor Edg-6

Gen-ID: 8698

NCBI Accession: NP_003766

UniProt: O95977