S1PR3 Antikörper (N-Term)

Produktnummer ABIN265059

Der Kaninchen Polyklonal anti-S1PR3 Antikörper (ABIN265059) detektiert spezifisch S1PR3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für S1PR3 Antikörper (N-Term) (ABIN265059)

Target: S1PR3 (Sphingosine-1-Phosphate Receptor 3 (S1PR3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S1PR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-S1PR3 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to EDG-3 / S1P3 / S1PR3.

Aufreinigung: Purified

Immunogen: Synthetic peptide derived from the N terminal of the EDG3 (S1P3) protein.

Anwendungsinformationen

Applikationshinweise: Western Blot: 5 - 10 μg/mL, Due to low expression of EDG receptors, we recommend use ofPierce Femto Signal substrate for western blot development.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu S1PR3

Target: S1PR3 (Sphingosine-1-Phosphate Receptor 3 (S1PR3))

Andere Bezeichnung: EDG-3 / S1P3

Hintergrund: Endothelial cell differentation gene-3 (EDG3) belongs to a family of G-protein couple receptors whose ligands are lysophospholipids. The ligand for EDG3 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family. They have been implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. The couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG3 is expressed in cardiovascular, leukocyte-containing and other tissues.Synonyms: EDG3, Endothelial differentiation G-protein coupled receptor 3, FLJ37523, FLJ93220, LPB3, MGC71696, S1P receptor 3, S1PR3, Sphingosine 1-phosphate receptor 3

Gen-ID: 1903

NCBI Accession: NP_005217

UniProt: Q99500