MAGI3 Antikörper

Produktnummer ABIN264918

Der Schaf Polyklonal anti-MAGI3 Antikörper (ABIN264918) detektiert spezifisch MAGI3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MAGI3 Antikörper (ABIN264918)

Target: MAGI3 (Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 3 (MAGI3))

Reaktivität: Human

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser MAGI3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAGI3 Antikörper

Spezifität: This antibody reacts to M A G I - 3 , P D Z 4 - 5 .

Aufreinigung: Purified

Immunogen: Recombinant protein corresponding to PDZ domain 4-5 of MAGI-3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1 - 10 μg/mL. Detects a 130 kDa band in cells transfected with full-lengthMAGI-3 protein.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu MAGI3

Target: MAGI3 (Membrane Associated Guanylate Kinase, WW and PDZ Domain Containing 3 (MAGI3))

Andere Bezeichnung: MAGI3

Hintergrund: Membrane-associated guanylate kinase with inverted orientation (MAGI3) is a novel, 130 kDa guanylate kinase which is part of a family of multi-PDZ domain containing guanylate kinases. These guanylate kinases are localized to epithelial cell tight junctions. MAGI3 and PTEN/MMAC cooperate to modulate the kinase activity of AKT/protein kinase B (PKB). MAGI3 positions the PTEN/MMAC phosphatase to specific subcellular locations that are involved with the regulation of cell proliferation and survival. MAGI3, as well as other proteins in this family, are made up of an N-terminal guanylate kinase domain, followed by a WW domain, named for two conserved tryptophan residues and first identified as two repeats in mouse YAP65, which is then followed by 6 PDZ domains.Synonyms: MAGI-3, Membrane-associated guanylate kinase, Membrane-associated guanylate kinase inverted 3, WW and PDZ domain-containing protein 3

Gen-ID: 260425

NCBI Accession: NP_001136254

UniProt: Q5TCQ9