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Antikörper
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anti-Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) Antikörper
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) Antikörper
| Antigen |
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| Synonyme |
CD16, FCG3, CD16A, FCGR3, IGFR3, FCR-10, FCRIII, FCGRIII, FCRIIIA |
| Klonalität |
Monoklonal (MEM-168) |
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Wirt
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Reaktivität
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Human (183), Schwein (11), Primaten (9), Primate (6), Pavian (5), Cynomolgus (5), Affe (5), Rhesusaffen (5), Maus (4), Schimpanse (1), Marmoset (1)
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Applikation
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Durchflusszytometrie (FACS) (190), Immunpräzipitation (IP) (46), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (27), Western Blot (WB) (18), Funktionale Studien (Func) (15), Immunhistochemie (Paraffinschnitte) (IHC (p)) (9), Immunzytochemie (ICC) (5), Immunfluoreszenz (IF) (4), Blockierende Antikörper (Inhibition) (3), ELISA (3), Enzyme Immunoassay (EIA) (3), ELISA (Detektionsantikörper) (2), Immunhistochemie (IHC) (2)
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| Produktnummer |
ABIN238452 |
| Menge |
0.1 mg (1.0 mg/ml) |
| Preis |
180,00 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 7 bis 10 Werktagen |
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Produktmerkmale
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Synonyms: IgG Fc receptor III-2, Fc-gamma RIII-alpha, FcR-10, CD16a, FCGR3A, FCG3, IGFR3, Fc-gammaRIIIa, FcRIIIa, Fc-gamma RIII, Low affinity immunoglobulin gamma Fc region receptor III-A
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Weitere Bezeichnung
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CD16
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Swiss-Prot
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P08637
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Immunogen
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Human granulocytes.
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Kreuzreaktivität
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Human
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Isotyp
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IgM
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Klon
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MEM-168
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Beschreibung
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CD16 (FcγRIII) is a 50-80 kDa glycoprotein serving as a low affinity IgG receptor. HumanFcγRIII is expressed in two forms FcγRIII-A and -B. FcγRIII-A is a transmembrane protein ofmonocytes, macrophages, NK cells and a subset of T cells. It is associated with FcεRI-γsubunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcγRIII-Ais associated, moreover, with FcεRI-β subunit. Besides IgG, FcεRI-A can be triggered alsoby oligomeric IgE. FcγRIII-B is a GPI-linked monomeric receptor expressed on neutrophilsand is involved in their activation and induction of a proadhesive phenotype.
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Spezifität
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The antibody MEM-168 reacts with CD16 antigen (isoform CD16a). CD16a (FcγRIIIA, 50-65kDa) is a transmembrane form of CD16, expressed on NK-cells, monocytes andmacrophages. Species: Human, Non-Human Primates, Porcine. Others not tested.
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Applikationshinweise
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Suitable for Flow Cytometry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Konzentration
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1.0 mg/ml
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Reinigung
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Purified
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Buffer
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PBS with 15 mM sodium azide as preservative.
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Lagerung
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Forschungsgebiet
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Stammzellen, Hämopoetische Vorläufer, Hämatopoetische Stammzellen, CD Antigene, Oberflächenrezeptoren der Immunzellen
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A)", Typ "Antikörper" finden
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Wirte
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Maus (196), Ratte (7), Kaninchen (1)
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Reaktivitäten
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Human (183), Schwein (11), Primaten (9), Primate (6), Pavian (5), Cynomolgus (5), Affe (5), Rhesusaffen (5), Maus (4), Schimpanse (1), Marmoset (1)
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Applikationen
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Durchflusszytometrie (FACS) (190), Immunpräzipitation (IP) (46), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (27), Western Blot (WB) (18), Funktionale Studien (Func) (15), Immunhistochemie (Paraffinschnitte) (IHC (p)) (9), Immunzytochemie (ICC) (5), Immunfluoreszenz (IF) (4), Blockierende Antikörper (Inhibition) (3), ELISA (3), Enzyme Immunoassay (EIA) (3), ELISA (Detektionsantikörper) (2), Immunhistochemie (IHC) (2)
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Konjugate
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Biotin (25), FITC (24), PE (21), Alexa Fluor 700 (4), Pacific Blue (4), RPE (4), Alexa Fluor 488 (3), PE,Cy5 (3), PerCP (3), APC (2), APC,Cy7 (2), Alexa Fluor 647 (2), Cy5.5,PE (2), EFluor 450 (2), EFluor 605NC (2), PE,Cy7 (2), PerCP,Cy5.5 (2), SPRD (2), PE-Dyomics 647 (1), RPE,Cy5 (1)
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Alternativen 
